What Is VIP?
VIP (Vasoactive Intestinal Peptide) is a naturally occurring neuropeptide first isolated from the intestine and widely distributed throughout the brain, lungs, immune system, and cardiovascular system. It is studied for its role in regulating immune response, neuroprotection, respiratory function, and vascular health across multiple research models.
Mechanisms of Action
Immune regulation and anti inflammatory effects through modulation of cytokine production, helping balance immune signaling and reduce chronic inflammation patterns in inflammatory and autoimmune models.
Neuroprotection and brain health support by promoting neuronal survival signaling and potentially enhancing cognitive function endpoints in neurodegeneration related research.
Smooth muscle relaxation and respiratory benefits via bronchodilation and vasodilation effects, improving oxygen delivery and circulation parameters in respiratory and cardiovascular research contexts.
Endothelial support and cardiovascular health signaling by improving blood flow, reducing oxidative stress, and supporting vascular integrity in circulation focused models.
Benefits
Inflammatory and autoimmune disease management interest in models involving sarcoidosis, rheumatoid arthritis, and chronic inflammatory syndromes.
Respiratory support interest for COPD, asthma, and pulmonary fibrosis related models through airway function support and inflammation reduction signaling.
Neuroprotection and cognitive enhancement interest in models focused on Alzheimer’s, Parkinson’s, and broader neuroinflammatory conditions.
Cardiovascular benefits signaling that may support circulation, vascular health, and endothelial function in hypertension and metabolic context research.
Dosing
Level | Dose |
|---|---|
Low | 50 mcg/day |
Average | 150 to 250 mcg/day |
High | 500 mcg/day or more |
Safety Profile
VIP is commonly described as well tolerated in the referenced discussion, with most observed issues described as mild and dose dependent. Potential observations include flushing or light dizziness from vasodilation effects, transient low blood pressure in some individuals, and possible nasal irritation with intranasal administration. Because VIP can influence multiple physiological systems, additional caution and monitoring is commonly advised in contexts involving cardiovascular disease, blood pressure instability, or immune dysregulation.
Stacking
Pre-Workout Pump Stack
VIP
Tadalafil
Gut Support Stack
VIP
BPC-157
Oral BPC-157
KPV
Oral KPV
Disclaimer: The information provided is intended solely for educational purposes and should not be considered a replacement for professional medical advice. All compounds referenced are not for human consumption.
